Could osteoporosis cause another broken bone?

A broken bone caused by a minor fall or lifting something the wrong way could be a sign you have osteoporosis, a bone disease that can cause your bones to become fragile.

If your osteoporosis gets worse, your bones could become weaker and you could experience a fracture that wouldn't occur in normal bone. Think about how any of these fractures may impact your health. Are you doing all you can do to help reduce your risk of future fractures due to osteoporosis?

Where could you suffer your next broken bone due to osteoporosis?

Upper Arm
Spine
Pelvis
Hip
Wrist
Ankle
Upper Arm
(PROXIMAL HUMERUS)

A fracture in the upper arm often occurs due to a fall. Symptoms include severe pain, a severely swollen shoulder, and very limited ability to move the shoulder.

While most of these fractures do not require surgical repair, surgery may be needed if bone fragments are shifted out of position.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Spine

Sometimes the result of a fall or lifting something heavy the wrong way, an acute spine (vertebral compression) fracture can cause sudden severe back pain. Multiple spine fractures can lead to loss of height and a severely rounded upper back (a dowager’s hump).

Most people who suffer a vertebral compression fracture get better within 6 to 8 weeks without specific treatment to repair the fracture. If you have severe pain that does not respond to initial treatment measures, then surgery may be considered.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Pelvis

Can occur when pelvic bone weakened by osteoporosis gives way with only body weight, often with no significant fall. Symptoms include groin and buttock pain, or pain when trying to walk.

Treatment may include bed rest, physical therapy, and progressive increase in walking. Inpatient hospitalization or nursing care may be needed to assist with daily activities.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Hip

Usually happens in the upper part of the thighbone near where it fits into the hip joint, typically as the result of a fall or direct blow. The patient with a hip fracture will have pain over the outer upper thigh or in the groin. There will be significant discomfort with any attempt to flex or rotate the hip.

Patients may be discharged from the hospital to their home or find that a stay in a rehabilitation facility is necessary to assist them in regaining their ability to walk.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Wrist

Often caused by falling on an outstretched arm, symptoms include immediate pain, tenderness, bruising, and swelling. In many cases, the wrist hangs in an odd or bent way (deformity).

A broken wrist can take about 6 weeks to heal, but full recovery should be expected to take at least a year. Depending on the fracture, treatment may involve a cast or surgery to implant pins, plates, and screws to help the bones mend.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Ankle

Can be caused by twisting or rolling the ankle. Symptoms of a fracture include immediate and severe pain, swelling, bruising, tenderness to touch, and inability to put any weight on the injured foot.

Depending on the severity of the broken bone, treatment may involve a high-top shoe, a cast, or surgery to reposition bone fragments and/or install screws, rods, or plates.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

This material is intended for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Click a circle to learn more about each type of fracture

Osteoporosis can put you at risk of breaking a bone

If you have osteoporosis, some factors that can put you at higher risk for breaking a bone include:

As you get older, your risk of fracture due to osteoporosis goes up.

According to the National Osteoporosis Foundation, all postmenopausal women and men age 50 and older should be evaluated for osteoporosis risk in order to determine the need for BMD testing and/or spine imaging.

The effect of FORTEO on fractures has not been studied in men.

If you have osteoporosis that has progressed to the point of a fracture, your disease could be severe.

  • Nearly 20% of women who break a bone in their spine due to osteoporosis will have another spine fracture within 12 months.
  • Women who have had a hip fracture due to osteoporosis are 4 times more likely to have another.

This is measured by your T-score, as shown in the chart. The lower, or more negative, your T-score (eg, –2.5 or lower), the more likely you are to be at high risk for fracture due to osteoporosis.

What does your T-score mean?
Your T-score compares your BMD to the average BMD in young adults. Osteoporosis is defined as a T-score of –2.5 or lower.

These are not all the risk factors for a broken bone due to osteoporosis. Talk to your healthcare professional to learn more and ask if FORTEO is right for you.

Learn more about osteoporosis and steps you can take to help reduce your risk of future fractures due to osteoporosis.
FORTEO is a prescription medication used in both men and postmenopausal women with osteoporosis who are at high risk for having broken bones, or fractures. FORTEO is used in both men and women with osteoporosis due to use of glucocorticoid medicines, such as prednisone, for several months, who are at high risk for having broken bones, or fractures. FORTEO can be used by people who have had a fracture related to osteoporosis, or who have several risk factors for fracture, or who cannot use other osteoporosis treatments.

SAFETY INFORMATION AND BOXED WARNING

What is the most important information I should know about FORTEO?

Warning: Potential Risk of Osteosarcoma

Possible bone cancer. During drug testing, the medicine in FORTEO caused some rats to develop a bone cancer called osteosarcoma. In people, osteosarcoma is a serious but rare cancer. Osteosarcoma has rarely been reported in people who took FORTEO. It is not known if people who take FORTEO have a higher chance of getting osteosarcoma. Before you take FORTEO, you should tell your healthcare provider if you have Paget's disease of bone, are a child or young adult whose bones are still growing, or have had radiation therapy.

Who should not take FORTEO?

  • You should not take FORTEO for more than 2 years over your lifetime.
  • Do not use FORTEO if you are allergic to any of the ingredients in FORTEO. Serious allergic reactions have been reported.

What should I tell my healthcare provider before taking FORTEO?

  • Before you take FORTEO, you should tell your healthcare provider if you have a bone disease other than osteoporosis, have cancer in your bones, have trouble injecting yourself and do not have someone who can help you, have or have had kidney stones, have or have had too much calcium in your blood, take medications that contain digoxin (Digoxin, Lanoxicaps, Lanoxin), or have any other medical conditions.
  • You should also tell your healthcare provider, before you take FORTEO, if you are pregnant or thinking about becoming pregnant. It is not known if FORTEO will harm your unborn baby. If you are breastfeeding or plan to breastfeed, it is not known if FORTEO passes into your breast milk. You and your healthcare provider should decide if you will take FORTEO or breastfeed. You should not do both.

What are the possible side effects of FORTEO?

  • FORTEO can cause serious side effects including a decrease in blood pressure when you change positions. Some people feel dizzy, get a fast heartbeat, or feel faint right after the first few doses. This usually happens within 4 hours of taking FORTEO and goes away within a few hours. For the first few doses, take your injections of FORTEO in a place where you can sit or lie down right away if you get these symptoms. If your symptoms get worse or do not go away, stop taking FORTEO and call your healthcare provider. FORTEO may also cause increased calcium in your blood. Tell your healthcare provider if you have nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs there is too much calcium in your blood.
  • Common side effects of FORTEO include nausea, joint aches, pain, leg cramps, and injection site reactions including injection site pain, swelling and bruising. These are not all the possible side effects of FORTEO. You are encouraged to report negative side effects of Prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Additional safety information about FORTEO

  • There is a voluntary patient registry for people who take FORTEO. The purpose of the registry is to collect information about the possible risk of osteosarcoma in people who take FORTEO. For information about how to sign up for this patient registry, call 1-866-382-6813 or go to www.forteoregistry.org.
  • The FORTEO Delivery Device has enough medicine for 28 days. It is set to give a 20-microgram dose of medicine each day. Before you try to inject FORTEO yourself, a healthcare provider should teach you how to use the FORTEO Delivery Device to give your injection the right way. Inject FORTEO one time each day in your thigh or abdomen (lower stomach area). Do not inject all the medicine in the FORTEO Delivery Device at any one time. Do not transfer the medicine from the FORTEO Delivery Device to a syringe. This can result in taking the wrong dose of FORTEO. If you take more FORTEO than prescribed, call your healthcare provider. If you take too much FORTEO, you may have nausea, vomiting, weakness, or dizziness.

How should I store FORTEO?

  • Keep your FORTEO Delivery Device in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze the FORTEO Delivery Device. Do not use FORTEO if it has been frozen. Do not use FORTEO after the expiration date printed on the delivery device and packaging. Throw away the FORTEO Delivery Device after 28 days even if it has medicine in it (see the User Manual).
TE Con ISI 09Sep2013

For more safety information, please see Medication Guide and Prescribing Information, including Boxed Warning regarding osteosarcoma. See User Manual that accompanies the delivery device.

SAFETY INFORMATION AND BOXED WARNING

MORE
LESS

What is the most important information I should know about FORTEO?

Warning: Potential Risk of Osteosarcoma

Possible bone cancer. During drug testing, the medicine in FORTEO caused some rats to develop a bone cancer called osteosarcoma. In people, osteosarcoma is a serious but rare cancer. Osteosarcoma has rarely been reported in people who took FORTEO. It is not known if people who take FORTEO have a higher chance of getting osteosarcoma. Before you take FORTEO, you should tell your healthcare provider if you have Paget's disease of bone, are a child or young adult whose bones are still growing, or have had radiation therapy.

Who should not take FORTEO?

  • You should not take FORTEO for more than 2 years over your lifetime.
  • Do not use FORTEO if you are allergic to any of the ingredients in FORTEO. Serious allergic reactions have been reported.

What should I tell my healthcare provider before taking FORTEO?

  • Before you take FORTEO, you should tell your healthcare provider if you have a bone disease other than osteoporosis, have cancer in your bones, have trouble injecting yourself and do not have someone who can help you, have or have had kidney stones, have or have had too much calcium in your blood, take medications that contain digoxin (Digoxin, Lanoxicaps, Lanoxin), or have any other medical conditions.
  • You should also tell your healthcare provider, before you take FORTEO, if you are pregnant or thinking about becoming pregnant. It is not known if FORTEO will harm your unborn baby. If you are breastfeeding or plan to breastfeed, it is not known if FORTEO passes into your breast milk. You and your healthcare provider should decide if you will take FORTEO or breastfeed. You should not do both.

What are the possible side effects of FORTEO?

  • FORTEO can cause serious side effects including a decrease in blood pressure when you change positions. Some people feel dizzy, get a fast heartbeat, or feel faint right after the first few doses. This usually happens within 4 hours of taking FORTEO and goes away within a few hours. For the first few doses, take your injections of FORTEO in a place where you can sit or lie down right away if you get these symptoms. If your symptoms get worse or do not go away, stop taking FORTEO and call your healthcare provider. FORTEO may also cause increased calcium in your blood. Tell your healthcare provider if you have nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs there is too much calcium in your blood.
  • Common side effects of FORTEO include nausea, joint aches, pain, leg cramps, and injection site reactions including injection site pain, swelling and bruising. These are not all the possible side effects of FORTEO. You are encouraged to report negative side effects of Prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Additional safety information about FORTEO

  • There is a voluntary patient registry for people who take FORTEO. The purpose of the registry is to collect information about the possible risk of osteosarcoma in people who take FORTEO. For information about how to sign up for this patient registry, call 1-866-382-6813 or go to www.forteoregistry.org.
  • The FORTEO Delivery Device has enough medicine for 28 days. It is set to give a 20-microgram dose of medicine each day. Before you try to inject FORTEO yourself, a healthcare provider should teach you how to use the FORTEO Delivery Device to give your injection the right way. Inject FORTEO one time each day in your thigh or abdomen (lower stomach area). Do not inject all the medicine in the FORTEO Delivery Device at any one time. Do not transfer the medicine from the FORTEO Delivery Device to a syringe. This can result in taking the wrong dose of FORTEO. If you take more FORTEO than prescribed, call your healthcare provider. If you take too much FORTEO, you may have nausea, vomiting, weakness, or dizziness.

How should I store FORTEO?

  • Keep your FORTEO Delivery Device in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze the FORTEO Delivery Device. Do not use FORTEO if it has been frozen. Do not use FORTEO after the expiration date printed on the delivery device and packaging. Throw away the FORTEO Delivery Device after 28 days even if it has medicine in it (see the User Manual).

For more safety information, please see Medication Guide and Prescribing Information, including Boxed Warning regarding osteosarcoma. See User Manual that accompanies the delivery device.

TE Con ISI 09Sep2013