Learn how fractures can
occur if your osteoporosis
has gotten worse.
Learn how osteoporotic fractures can occur and why now's the time to take action.
Learn how osteoporotic fractures can occur and why now's the time to take action.
Learn how fractures can
occur if your osteoporosis
has gotten worse.

What Is Osteoporosis and What Does It Mean for You?

Osteoporosis is a bone disease that can get worse over time. It can cause you to lose bone mineral density and bone mass, which can cause your bones to become fragile. You may not realize this is happening in your body because you can't feel your bones getting weaker.

If osteoporosis progresses, bones can become weak and you can experience a fracture that wouldn't occur in normal bone. The symptoms of your osteoporosis may not be visible unless you have a fracture, so you may not even know you have the disease until you break a bone or a test shows that you have low bone mineral density. And if you've had one broken bone due to osteoporosis, your risk for having another goes up.

Osteoporosis is a serious disease, not a normal part of aging. Although there's no cure for osteoporosis, you can take control by taking precautions and tracking how your osteoporosis is treated to help protect yourself from fractures.

Terms Your Doctor May Use:

"Bone Mineral Density Test" "BMD Test" "DXA Scan"
All of these terms mean the same thing. The result of your BMD test is called a T-score and it helps a doctor assess the severity of osteoporosis.

You're Not Alone

There are 12 million Americans estimated to have osteoporosis—9.1 million are women and 2.8 million are men. Women are more susceptible to osteoporosis because they can lose up to 15% of their bone mineral density in the 5 to 7 years after menopause.

  • Approximately 1/2 of all women aged 50 years or older will suffer an osteoporotic fracture in their remaining lifetime.
  • Approximately 1/4 of all men aged 50 years or older will suffer an osteoporotic fracture in their remaining lifetime.

The effect of FORTEO on fractures has not been studied in men.

Assess Your Risk

Osteoporosis is sometimes known as a "silent" disease because it often has few warning signs or symptoms. That means you may not know you have it or that it's getting worse until after you've broken a bone. If you've had one fracture due to osteoporosis, it can lead to an increased risk of more fractures. Research studies have shown:

4x more likely to fracture again Women who have had a hip fracture due to osteoporosis are 4 times more likely to have another.
20% will fracture again in 12 months Nearly 20% of women who sustain a new spine fracture will have another spine fracture within 12 months.

If you have osteoporosis, some factors that can put you at higher risk for osteoporotic fracture include:

Your risk of osteoporotic fracture goes up with age.

History of Fracture
One fracture may put you at risk for future fractures.

Low Bone Mineral Density (BMD)
This is measured by your T-score.

These are not all the risk factors for osteoporosis. Talk to your healthcare professional to learn more.

Learn About Your T-score

Your T-score compares your BMD to the average BMD in young adults. Osteoporosis is defined as a T-score of -2.5 or lower. The lower, or more negative your T-score, the more likely you are to be at high risk for fracture due to osteoporosis.

Images copyright of Lilly

Communication Is Key

Use the interactive Doctor Discussion Guide to talk to your healthcare provider about your risk for a broken bone due to osteoporosis.

Get Started

Indications for FORTEO:

  • FORTEO is used in both men and postmenopausal women with osteoporosis who are at high risk for having broken bones or fractures.
  • FORTEO is used in both men and women with osteoporosis due to use of glucocorticoid medicines, such as prednisone, for several months, who are at high risk for having broken bones or fractures.
  • FORTEO can be used by people who have had a fracture related to osteoporosis, or who have several risk factors for fracture, or who cannot use other osteoporosis treatments.

FORTEO is a prescription medicine given as a 20-microgram once-daily dose available in a 2.4-mL delivery device for subcutaneous injection over 28 days.

Important Safety Information About FORTEO

What is the most important information I should know about FORTEO?


Possible bone cancer. During drug testing, the medicine in FORTEO caused some rats to develop a bone cancer called osteosarcoma. In people, osteosarcoma is a serious but rare cancer. Osteosarcoma has rarely been reported in people who took FORTEO. It is not known if people who take FORTEO have a higher chance of getting osteosarcoma. Before you take FORTEO, you should tell your healthcare provider if you have Paget's disease of bone, are a child or young adult whose bones are still growing, or have had radiation therapy.

Who should not take FORTEO?

  • You should not take FORTEO for more than 2 years over your lifetime.
  • Do not use FORTEO if you are allergic to any of the ingredients in FORTEO. Serious allergic reactions have been reported.

What should I tell my healthcare provider before taking FORTEO?

  • Before you take FORTEO, you should tell your healthcare provider if you have a bone disease other than osteoporosis, have cancer in your bones, have trouble injecting yourself and do not have someone who can help you, have or have had kidney stones, have or have had too much calcium in your blood, take medications that contain digoxin (Digoxin, Lanoxicaps, Lanoxin), or have any other medical conditions.
  • You should also tell your healthcare provider, before you take FORTEO, if you are pregnant or thinking about becoming pregnant. It is not known if FORTEO will harm your unborn baby. If you are breastfeeding or plan to breastfeed, it is not known if FORTEO passes into your breast milk. You and your healthcare provider should decide if you will take FORTEO or breastfeed. You should not do both.

What are the possible side effects of FORTEO?

  • FORTEO can cause serious side effects including a decrease in blood pressure when you change positions. Some people feel dizzy, get a fast heartbeat, or feel faint right after the first few doses. This usually happens within 4 hours of taking FORTEO and goes away within a few hours. For the first few doses, take your injections of FORTEO in a place where you can sit or lie down right away if you get these symptoms. If your symptoms get worse or do not go away, stop taking FORTEO and call your healthcare provider. FORTEO may also cause increased calcium in your blood. Tell your healthcare provider if you have nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs there is too much calcium in your blood.
  • Common side effects of FORTEO include nausea, joint aches, pain, leg cramps, and injection site reactions including injection site pain, swelling and bruising. These are not all the possible side effects of FORTEO. You are encouraged to report negative side effects of Prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Additional safety information about FORTEO

  • There is a voluntary patient registry for people who take FORTEO. The purpose of the registry is to collect information about the possible risk of osteosarcoma in people who take FORTEO. For information about how to sign up for this patient registry, call 1-866-382-6813 or go to www.forteoregistry.org.
  • The FORTEO Delivery Device has enough medicine for 28 days. It is set to give a 20-microgram dose of medicine each day. Before you try to inject FORTEO yourself, a healthcare provider should teach you how to use the FORTEO Delivery Device to give your injection the right way. Inject FORTEO one time each day in your thigh or abdomen (lower stomach area). Do not inject all the medicine in the FORTEO Delivery Device at any one time. Do not transfer the medicine from the FORTEO Delivery Device to a syringe. This can result in taking the wrong dose of FORTEO. If you take more FORTEO than prescribed, call your healthcare provider. If you take too much FORTEO, you may have nausea, vomiting, weakness, or dizziness.

How should I store FORTEO?

  • Keep your FORTEO Delivery Device in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze the FORTEO Delivery Device. Do not use FORTEO if it has been frozen. Do not use FORTEO after the expiration date printed on the delivery device and packaging. Throw away the FORTEO Delivery Device after 28 days even if it has medicine in it (see the User Manual).

For more safety information, please see Medication Guide and Full Prescribing Information, including Boxed Warning regarding osteosarcoma.

See Full Delivery Device User Manual that accompanies the Delivery Device.

TE Con ISI 09Sep2013